Also, “our findings — which focused only on prescription NSAIDs — might apply to over-the-counter NSAIDs as well,” Arfe said. “Although over-the-counter NSAIDs are typically used at lower doses and for shorter durations, they are sometimes available at the same doses as prescription NSAIDs and they may be inappropriately overused.” Still, the nature of the study can only point to an association between NSAID use and heart failure risk — it can’t prove cause-and-effect. And one expert believes that most patients who need an NSAID for their pain can safely continue using the drugs. The findings were reported Sept. 28 in the BMJ. According to the American Academy of Orthopaedic Surgeons (AAOS), NSAIDs decrease inflammation and pain by blocking an enzyme called cyclooxygenase. This enzyme comes in two forms, COX-1 and COX-2. COX-1 protects the stomach lining from digestive acids, while COX-2 is produced by injured or inflamed joints. bunion hair tieTraditional NSAIDs — like aspirin or ibuprofen — block the action of both COX-1 and COX-2, which is why some people suffer from stomach upset after taking them, the AAOS said. Newer NSAIDs like celecoxib (Celebrex) target only COX-2, and are referred to as COX-2 inhibitors. Doctors have been concerned for some time that NSAIDs might play a role in heart failure, because they cause people to retain sodium, explained Dr.
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Running on uneven surfaces can also cause an ankle swelling. Ankle sprains, tendinitis, as well as minor injuries to the ankle are some of the possible causes of ankle pain. In severe cases, enema could also be accompanied by skin changes, ulcers, etc. Sometimes, the swelling may get extended up to the calves and thighs as well. The primary cause of the swelling is the fluid retention in the cells. The treatment depends on what has caused the pain. Anyone who has regularly played sports, or jogged, will be aware of the most common sports injury―the ankle sprain. try this web-siteThrough this article let us see how to wrap a sprained ankle with bandage, along with the methods for treating a sprained ankle… Get Rid of Venom: If you have been stung by a wasp, you must take immediate steps to draw out the venom. Ice/Heat Pack: The choice between ice and heat packs is based on the effect they have on pain.
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